Slide 1
The Sapphire Biomolecular Imager
Redefining MORE
IMAGING MODALITIES:
fluorescence
Slide 2
The Sapphire Biomolecular Imager
Redefining MORE
IMAGING MODALITIES:
chemiluminescence
Slide 3
The Sapphire Biomolecular Imager
Redefining MORE
IMAGING MODALITIES:
phosphor imaging
Slide 4
The Sapphire Biomolecular Imager
Redefining MORE
PERFORMANCE:
resolution
Slide 5
The Sapphire Biomolecular Imager
Redefining MORE
PERFORMANCE:
sensitivity
Slide 6
The Sapphire Biomolecular Imager
Redefining MORE
PERFORMANCE:
wide dynamic range
Slide 7
The Sapphire Biomolecular Imager
Redefining MORE
APPLICATIONS:
chemiluminescent western blot
Slide 8
The Sapphire Biomolecular Imager
Redefining MORE
APPLICATIONS:
2D-DIGE
Slide 9
The Sapphire Biomolecular Imager
Redefining MORE
APPLICATIONS:
phosphor imaging
Slide 9
The Sapphire Biomolecular Imager
Redefining MORE
APPLICATIONS:
more...
previous arrowprevious arrow
next arrownext arrow

One Instrument, A Wealth of Capabilities

Whatever type of imaging your lab does—whether it’s the ubiquitous western blot, Southern blots of 2D DNA gels, visualizing gross morphology of tissues or small model animals, or something more unique—the Sapphire Biomolecular Imager will deliver outstanding, quantitative detection with NIR and RGB fluorescence, chemiluminescence, and phosphorimaging.
Fluorescent westerns with up to four color detection

Get faster workflows and more reliable quantitation

Sensitive chemiluminescent detection

Maximize your western blot workflow options

View and quantify 35S-labeled proteins in 2D gels
Perform proteomics analysis on metabolically-labeled samples
Phosphorimaging

Directly detect DNA for Sanger sequencing and footprinting
Track protein movement through tissue in small animals

Lymphatic antigen tracking in mouse hindpaw 

Visualize anatomical
structure


The next generation of laser scanning systems, the Sapphire Biomolecular Imager delivers unmatched flexibility and performance for today’s demanding labs.

With more imaging modalities than any other instrument currently on the market, the Sapphire’s four solid state lasers and patent-pending three-detector system enables an incredibly wide range of applications. And the intuitive, easy-to-use software ensures a smooth acquisition and analysis experience for all users.

  • Improved multiplex fluorescent detection (near IR and visible)
  • Chemiluminescent imaging, surpassing film
  • Higher sensitivity for lower limits of detection (femtograms)
  • Broad linear dynamic range for accurate quantitation
  • Ease-of-use with intuitive control software
Azure Sapphire Biomolecular Imager™LI-COR® Odyssey® CLxAmersham® Typhoon®
NIR Fluorescence
Visible Fluorescence
Phosphor Imaging
Chemiluminescence
(Similar sensitivity to film)
Resolution10µm21µm10µm
Dynamic Range> 6 logs4-6 logs> 5 logs
Price$$$$

LI-COR® and Odyssey® are registered trademarks of LI-COR®. Typhoon® is a registered trademark of GE Healthcare Bioprocess R&D AB. Amersham® is a registered trademark of GE Limited Liability Co.

More Quantitative Fluorescence Imaging

Improve your quantitation with the ability to reliably measure multiple proteins in a single blot, from very weak to very strong bands.

More Sensitivity with Chemiluminescence Imaging

Experience the speed and sensitivity of traditional film with 4-fold greater sensitivity and detection down to femtogram amounts of protein.

More Flexibility with Phosphor Imaging

Step away from the limitations of film-based autoradiography and get the wide dynamic range and high sensitivity of phosphor imaging-based detection.

More Applications

2D-DGE • FLUORESCENT PROTEIN NATIVE GEL • REPORTER GENE ASSAY • QUANTITATIVE WESTERN BLOT • NUCLEIC ACID GEL DOCUMENTATION • ELISA • IN-GEL WESTERN • PROTEIN GEL DOCUMENTATION • PROTEIN ARRAY • IN-CELL OR ON-CELL ELISA • DENSITOMETRY • CHEMILUMINESCENT ARRAY • QUANTITATIVE WESTERN BLOT • ELECTROPHORETIC MOBILITY ASSAY • CHEMILUMINESCENT WESTERN BLOT • IN-CELL WESTERNS • PHOSPHOR IMAGING • TISSUE SECTION IMAGING

Scientists are Raving about Sapphire

Great value, powerful, flexible, reliable. Buy it!

— John Streicher, Assistant Professor, Neuroscience, University of Arizona
"This is a high quality imager that has a strong value for the usability vs. price. The imager is highly programmable, supporting multiple applications, and returns sensitive and high quality data. The imager has also been reliable, with no errors, breakdowns, or problems. Adding to this, the sales staff, particularly David Grothen, are fantastic. They have worked with us, got us a great deal, and have been very supportive post-purchase. Buy it, you won't be sorry!"

Main work horse instrument

— Tim Jensen Research Analyst, University of North Carolina School of Medicine
“The Sapphire imager is one of our lab's main work horse instruments. It is used on a daily basis for fluorescent and chemiluminescent imaging of Western blots and plates. The image quality and resolution of the imager are top notch. The ability to image a single blot in multiple wavelengths is a great advantage as it saves precious samples, time and reagents. Customer support has been awesome and I would highly recommend this instrument to anyone looking to add fluorescent scanning to their lab."

Use it for fluorescent gels and western blots regularly

— Allen P. Liu, Ph.D. Associate Professor of Mechanical Engineering, University of Michigan
“My lab has a Sapphire Imager RGB-NIR with 4 lasers for over a year and a half now. This has been a workhorse for us as we use it for fluorescent gels and western blots regularly. My researchers have been happy with it and I am pretty happy with the imager."

Replaced our obsolete typhoon scanner

​— Sharyn Rossi, National Institutes of Health/National Institute on Aging
“We purchased the Sapphire imager to replace our obsolete typhoon scanner and could not be happier with the performance and ease of use. Equipped with multiple lasers, it is possible to probe for many proteins at high resolution and with great sensitivity. We primarily use the system for western blotting and fluorescent slide scanning and have had clear, publishable results. The software is easy to use and has many practical features. Customer service is amazing – they are always available, informative, and as scientists, they assist with troubleshooting experimental design and optimizing results. This product is highly recommended for anyone who routinely uses electrophoresis, cell-based, or slide-based analyses with fluorescent or chemiluminescent detection.”

Technical support without delay when asked

— Minhua Dou Huzhou, Nutrition and Health Industry Innovation Center, CAS
"Sapphire RGBIR is a powerful and quality laser scanner in our laboratory. Its high-performance laser light sources, high-sensitivity detector and 10μm highest resolution gives us high-quality data; Its multiplex fluorescence channels and CCD-based function makes us can develop several methods to verify and get an accurate result. For us, the most important thing of the large precision instrument besides good quality, performance is service. Azure’s good service is better than most of other manufacturers because of the professional regular service about twice a year and the technical support without delay when asked.”

Excellent scanning results, perfect service team.

— Peter Cheung, Hong Kong University
"The scanner is definitly the top model available on the market. It starts up fast, and doesnt need to warm up. The scanning is very sharp and time saving. It also gives a wide range of intensity dynamics. This machine gives us excellent publishing grade results. We recently relocated the machine, and our sales and service care manager Nicole gave us a lot of instruction on transporting and hand on hand calibration. She is very kind and responsible. We are all looking forward to cooperating with her in our coming new lab next year."

Documents

Document TypeDescription
BrochureSapphire Biomolecular Imager BrochureDOWNLOAD
Application NotePhosphor Imaging with the Sapphire Biomolecular ImagerDOWNLOAD
Application NoteDetecting Proteins In-Situ with In-Cell Western BlottingDOWNLOAD
Application NoteIncreasing Assay Efficiency with Four Color DetectionDOWNLOAD

Videos

Azure Sapphire Video

Mouse Imaging on the Azure Sapphire

Fluorescence Scanning on the Azure Sapphire

Experience the flexibility and performance of the Sapphire Biomolecular Imager for yourself. Use the form below to request a free quote or to learn more.

    Shopping cart
    There are no products in the cart!
    Continue shopping