Real-time PCR Systems

The Cielo is a robust and durable qPCR machine with smart protocols for high-quality data

Meet the Cielo

Real-time PCR Machine

The Azure Cielo qPCR System is a reliable system packaged with innovative and high-performance optical technology. Three or six standard channels allow you to analyze a variety of commercially available dyes that are already in your workflow.

The Cielo’s novel fiber optic detection system allows for enhanced sensitivity and speed. The Cielo was designed around individual well scanning, comprising of two sets 16 fiber optics. Channel-specific excitation and emission light
emitting diode (LED) light sources ensure that specific wells on the qPCR plate are illuminated, increasing sensitivity and reducing background noise.

Scientist using screen on Azure Cielo qPCR system
The Cielo qPCR system's onboard software is operated by a 10.2″ touchscreen, minimizing footprint and saving you bench space.

Compare qPCR Models (Dyes/Probes)

ParameterCielo 6Cielo 3
Sample capacity (Wells)96 wells
Compatible Plates/Tubes96-well plates and tubes, 8- or 12-well strips and single tubes
Reaction Volume1-50 uL (1-65 recommended)
Dynamic Range10 Logs
Excitation SourceLED Excitation range: 450-730 nmLED Excitation range: 450-730 nm, 610-700 nm
Detection Channels63
MultiplexingUp to 6 targetsUp to 3 targets
Reaction Temperature4°C to 99.9°C
Max Block Ramp Rate6°C/sec
Average Sample Ramp Rate4°C/Sec
Temperature Uniformity±0.2°C
Temperature Accuracy±0.1°C
Custom Dye/Chemistry
Onboard Memory32 GB Equivalent to 20,000 experiments
Unit dimensions (W x H x D)​30.5 cm x 50.8 cm x 43.2 cm / 12” x 20” x 17"
Weight​22.7kg / 50 lbs
Power requirements100-240 VAC, 8A; Consumption: 0.8kW (800 Watts)
ConnectivityUSB, Wifi, Ethernet
CertificationsCE Certified, TUV Certified

qPCR Software

A Look at Cielo Manager

Cielo Manager is a superior, PC-compatible qPCR analysis software designed to let you set up, run, and analyze your qPCR data from your personal computer. The Cielo easily connects via Wi-Fi, ethernet, USB, or LAN, which allows Cielo Manager to send email notifications after completed runs. You can also remotely access protocols and files.

qPCR System Applications

Shop qPCR Plastics

Best-in-class plates, tubes, seals, and accessories for PCR and qPCR experiments.

Resources

Document TypeDescription
BrochureCielo BrochureDOWNLOAD
Application NoteGoTaq Enviro Wastewater SARS-CoV-2DOWNLOAD

Citations featuring Cielo qPCR System

For Research Use Only

Fast, accurate, and reliable qPCR results are in reach. Contact us today to get pricing on the Cielo qPCR System.


Headquarters:
Azure Biosystems, Inc.
6747 Sierra Court, Suite A-B
Dublin, CA 94568
United States

Tel: (925) 307 7127
Fax: (925) 905-1816
Info@azurebiosystems.com

Azure Biosystems Pte. Ltd.
68 Circular Road, #02-01
Singapore, 049422

Copyright © 2026 Azure Biosystems Inc.
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