It’s time to think outside the blot (and gel)

Azure Sapphire FL Biomolecular Imager with lid open

The new Azure Sapphire FL Biomolecular Imager uses 5 micron resolution and countless laser and filter combinations to allow you to image so much more than before. Scan as many as 6 membranes or 6 96-well plates at a time. An additional 4 cm of
clearance above the glass allows for small animal imaging and tissue imaging, giving you a plethora of imaging options.


Experience the flexibility for yourself

With an upgraded resolution of 5 μm, the new Sapphire FL Biomolecular Imager lets you capture so much more than gels and Western blots. It allows you to run in-cell Westerns, and document microarray slides, tissue samples, 2D gels, plus more, all with NIR and visible fluorescence, chemiluminescence, and phosphor imaging. An adjustable focal plane enables scanning of thick samples, such as lung tissue.

Here are just a few examples of what we’ve imaged on the Sapphire FL—now imagine what the Sapphire FL can do for your research…

In-cell Western Blots
Z-stack Images
In-cell Western image with black 96-well plate. Imaged using RGB Azure Sapphire using 3 lasers.

In-cell Western Blots

50-micron scan of the same flower was merged in the Sapphire FL Capture Software to view all areas of focus at once.

50-micron scan of a flower scanned from 0 to 6 mm with 1 mm adjustments. Merged in Sapphire FL Capture Software to view all areas of focus at once.


Bee head scanned with Azure Sapphire

Bee Head

Motor neuron scanned with Azure Biosystems

Motor Neurons

Pine cone scanned using 2-channel imaging on Azure Biosystems

Pine Cone

Slides of mouse brain scanned with Azure Sapphire

Mouse Brain

Composite image of a bee leg scanned at 10 microns with 784nm and 488nm lasers, using Azure Biosystems Sapphire Biomolecular Imager

Bee Leg

Composite image of baby tomato slice scanned at 10 micron using 488nm and 658nm lasers on Azure Sapphire Biomolecular Imager

Mini Tomato

Mini Leaf Fern Prothallia & Sporangia scanned at 10 micron using Azure Sapphire


Scan of a lung imaged using 520nm and 784nm lasers from the Azure Sapphire Biomolecular Imager at 10 micron


Pine Cone on Slide

Whole Tissues Stained and Placed Directly on the 25x25 cm Field of View

Mouse lung tissue slide stained with 650-Smooth Muscle Actin (SMA). Imaged on the Sapphire FL with 638nm laser modules at 5um (RIGHT). Mouse lung tissue slide stained with 550 Vascular endothelial (VE)-cadherin. Imaged on the Sapphire FL with 532nm laser module at 5um (LEFT).

Mouse Lung Tissue Slide

Sheep Kidneys on Scanner Pre Imaging

Sheep kidney scan on sapphire

Sheep Kidney

Chicken Heart

Mouse Lung Tissue Slide

Mouse Lung Tissue Slide


Sheep Tongue (top)

Sheep Tongue (bottom)

Cow Stomach

Flexibility with a Capital "FL"

Unlimited Laser and Filter Wavelength Combinations

Scientist changing optical modules on the new Azure Sapphire FL
Pick the modules that support your research. Changing the optical modules on the new Sapphire FL is simple and easy. The unique mechanism makes selecting lasers to match your dyes finally possible. Easily swap lasers, filters, and/or entire optical modules in under two minutes to suit the needs of your experiment.

Application Flexibility


Document TypeDescription
BrochureSapphire FL Product BrochureDOWNLOAD
InfographicHow Do You View?DOWNLOAD
BrochureSapphire Applications OverviewDOWNLOAD
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