Azure Cielo™ Dx real-time PCR

qPCR system for in-vitro diagnostic use, bringing accuracy and sensitivity for research

Why Choose Azure Cielo Dx



Operates with 6-target detection and allows for the flexibility you need at your fingertips


Variety of Dyes

The option of 3 or 6 standard channels lets you analyze a variety of commercially available dyes, already in your workflow.

in vitro diagnostics


Registered with the U.S. FDA as Class II 510(k) exempt devices


IVD for EU

CE marked under the In Vitro Diagnostic Medical Devices Directive (98/79/EC)*

*Cielo Dx is available for distribution and use in the following countries: Austria, Belgium, Bulgaria, Croatia, Cyprus, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, the Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden

Key Features

Quickly Set up and Confirm Plate Layout

Each well is color coded by sample type, biological replicate, and technical replicate. Well type and standard curve values are also easily visible.

View Each Individual Amplification Trace by Target or Sample

NIR lasers keep signal high and background low. Our high-performance multiplex NIR lasers and filters deliver robust excitation energy which maximizes emission strength for maximum sensitivity. 

2D "Heat Map" of Samples

This feature makes it easy to review your samples and quickly understand your data.

Optical Design Eliminates the Need for ROX

The Cielo’s efficient well-based scanning technology scans multiple data points within each well, eliminating the need for normalization dyes such as ROX.

Amplification curves generated using human genomic DNA template along with human GAPDH primers and a no ROX SYBR Green qPCR mix.

Approximately 100,000 Data Points/Wells Using Total Well Detection Technology

Competitive systems only acquire 1 pixel/well compared to the Cielo’s ability to capture approximately 100,000 pixels/wells, enabling accurate, reproducible and sensitive representation of fluorescent intensities from each qPCR well.

Built for Reproducibility

High-quality engineering includes Peltier-based thermal block system designed for superior thermal cycling and unmatched optical design to ensure every run is accurate and reproducible.

Unparalleled uniformity. Amplification curves for 96 replicates shown on a linear plot

(A) and a logarithmic plot (Figure B). In each well, 105 copies of GAPDH template were amplified in the presence of GAPDH primers and BioRad™ Sso Advanced SYBR Green Mix®. Average Cq = 19.1, Coefficient of variance (Cv)= 0.002.

Compare Systems

Onboard software operated by a 10.2" touchscreen minimizes footprint and saves you bench space

Scientist using screen on Azure Cielo qPCR


What Scientists are Saying

"Good machine, easy to use."


Good machine, easy to use, highly accurate and easy to take the results but the difficulty in test timing it takes an hour and 37 minutes to complete the run.


Document TypeDescription
BrochureAzure Cielo Dx BrochureDOWNLOAD
Press ReleaseAzure Biosystems Launches Azure Cielo Dx for In-vitro Diagnostic UseDOWNLOAD
Application NoteOptical Design Eliminates the Need for ROX Passive Reference DyeDOWNLOAD
Application NoteSensitive and Accurate Single-Copy Amplicon DetectionDOWNLOAD
Application NoteData for 6-Channel Multiplex qPCRDOWNLOAD
Application NoteUsing the Azure Cielo™ Real-Time PCR System for SARS-CoV-2 viral RNA detectionDOWNLOAD
Application NoteGoTaq Enviro WastewaterDOWNLOAD
User ManualAzure Cielo Dx User ManualDOWNLOAD


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