Cielo™ Dx qPCR System for In vitro Diagnostics (IVD)

Why Choose Azure Cielo Dx

Accuracy

Operates with 6-target detection and allows for the flexibility you need, right at your fingertips

Dye Varieties

The option of 3 or 6 standard channels lets you analyze a variety of commercially available dyes, already in your workflow.

IVD for USA

Cielo Dx is registered with the U.S. FDA as Class II 510(k) exempt devices

CE for EU

CE marked under the In Vitro Diagnostic Medical Devices Directive (98/79/EC)*

*Cielo Dx is available for distribution and use in the following countries: Austria, Belgium, Bulgaria, Croatia, Cyprus, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, the Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden

Key Features

Quickly Set up and Confirm Plate Layout

Each well is easily labeled with three identifiers:

Well Type,
Sample ID, and
Dye/Target.

These identifiers are used for data analysis and easy visualization of the amplification and standard curves.

View Each Individual Amplification Trace by Target or Sample

Easily view all of your data at once or select specific wells/targets to view a subset of your data.

Visualize amplification curves in linear or log view and change the color of the amplification curves to easily distinguish the data by Sample ID or target.

2D Sample Heat Map

Wells are colored in a heat map style based on Cq value, with the lowest Cq values in green and highest Cq values in red. Quickly review Cq values, and assess data uniformity and separation between dilutions.

Optical Design Eliminates the Need for ROX

Well-based excitation and color-specific LED light sources ensure the excitation efficiency in every well for every channel is the same. Coupled with the Cielo’s scanning technology which collects multiple data points from each well, the well-based optical design eliminates the need for normalization dyes such as ROX.

Approximately 100,000 Data Points/Wells Using Total Well Detection Technology

Competitive systems only acquire 1 pixel/well compared to the Cielo’s ability to capture approximately 100,000 pixels/wells, enabling accurate, reproducible and sensitive representation of fluorescent intensities from each qPCR well.

Built for Reproducibility

High-quality engineering includes Peltier-based thermal block system designed for superior thermal cycling and unmatched optical design to ensure every run is accurate and reproducible.

Compare Systems

Azure Cielo 3 Dx

Azure Cielo Dx qPCR System for IVD

SAMPLE CAPACITY (WELLS)
96

COMPATIBLE PLATES/TUBES
96-WELL PLATES & TUBES AND 8
OR 12-WELL STRIPS & SINGLE TUBES

REACTION VOLUME
1-150 uL (10-65 uL recommended)

DYNAMIC RANGE
10 LOGS

EXCITATION SOURCE
LED, EXCITATION RANGE: 450–580NM AND 610–700NM

DETECTION CHANNELS
3

MULTIPLEXING
UP TO 3 TARGETS

REACTION TEMPERATURE
4°C to 99.9°C

MAX. BLOCK RAMP RATE
6°C/sec

AVG. SAMPLE RAMP RATE
4°C/SEC

TEMPERATURE UNIFORMITY
±0.2°C

TEMPERATURE ACCURACY
±0.1°C

CUSTOM DYE/CHEMISTRY
✓

ONBOARD MEMORY
32GB Equivalent to 20,000 EXPERIMENTS

CONNECTIVITY
USB, WI-FI, ETHERNET

FOOTPRINT (W/D/H)
12″ X 20″ X 17″ (30.5 X 50.8 X 43.2 CM)

Azure Cielo 6 Dx

Azure Cielo Dx qPCR System for IVD

SAMPLE CAPACITY (WELLS)
96

COMPATIBLE PLATES/TUBES
96-WELL PLATES & TUBES AND 8
OR 12-WELL STRIPS & SINGLE TUBES

REACTION VOLUME
1-150 uL (10-65 uL recommended)

DYNAMIC RANGE
10 LOGS

EXCITATION SOURCE
LED, EXCITATION RANGE: 450–730NM

DETECTION CHANNELS
6

MULTIPLEXING
UP TO 6 TARGETS