Azure Imagers vs. Protein Simple Fluorchem®

Trade in your FluorChem System, and upgrade to an Azure Imaging system for quantitative, reproducible Western blots

Why AZURE IMAGERS?

Innovative Design Translates into Better Performance

It should be no surprise that instrument design can greatly impact instrument performance. At Azure Biosystems, we focus on using technological innovation to deliver instruments that really impact a scientist’s work. Our design choices simplify workflows and improve performance without significantly impacting price.

Direct, mirror-free detection delivers better sensitivity

One way the design of Azure Imagers delivers better performance than FluorChem imagers is through our direct-mirror-free detection. We place our CCD sensor close to the sample to maximize light collection efficiency and, thus, sensitivity. In contrast, the FluorChem sensor is placed much farther away from the sample, reducing sensitivity.

In addition, FluorChem does not directly detect light from the sample, but rather the light is reflected onto the sensor using a mirror, which further reduces sensitivity.

Decrease in light intensity (inverse-square law)
NIR lasers increase sensitivity and reduce background

The use of laser light sources for NIR illumination in Azure Imaging Systems further increases sensitivity. Lasers deliver an inherently narrower excitation band than LEDs—they emit a coherent, collimated beam of light. Lasers avoid the overlap in excitation and emission signals that can occur with LED light sources. This results in ultra-low background signal, enabling faster, more sensitive NIR fluorescence detection.

NIR lasers used in Azure Imagers keep signal high and background low. The robust excitation energy delivered by lasers maximizes emission strength for optimal detection sensitivity.

Azure Imagers vs. Fluorchem systems:

Why Our Customers Love Our Imagers

lane detection

Best Image Quality

Modern, multimodal CCD camera that produces high-quality, publication-ready images through sensitive chemiluminescence detection

compact

Small Size

Smaller footprint than an average desktop printer. Leaves you more space to do what you do best. Azure Imager size: 42 x 56 x 33 cm (W x H x D)

user friendly

Excellent Customer Support

Global support team is here to support your questions about imaging, analysis or applications

Better Images and Better Support

Not sure how your discontinued FluorChem model stacks up? Find your model below and compare it with an Azure Imager 

Azure-600

Azure 600

Azure-400

Azure 400

Azure-300

Azure 300

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TRUE LIGHT

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blue LIGHT

TRUE LIGHT

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TRUE LIGHT

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Upgrades available for chemiluminescence, NIR fluorescence and RGB fluorescence.

All Azure customers have access to free software updates, easy-to-follow software tutorials, along with our best-in-class support team.

Bench-friendly, Space-saving Footprint

AZI vs. FluorChem size comparison

Footprint of the 600® Imager (42 x 56 x 33 cm; W x H x D) vs. the FluorChem System (dotted line, 12.6 x 24.5 x 24.5 in)

More about Azure Imagers

All Azure Imaging Systems offer:
  • Focus-free imaging, no-positioning necessary
  • One-touch workflows—select your application and the instrument chooses the appropriate light source and filters
  • AzureSpot Analysis Software for powerful and streamlined quantitative analysis
Select instruments offer:
  • Chemiluminescent detection that’s just as sensitive as film, but easier and more quantitative
  • Two NIR lasers (660 nm and 785 nm) that keep signal high and background low
  • Efficient multiplex detection with three visible fluorescence channels and/or two NIR fluorescence channels
  • An optional Q-module that adds the capability to perform total protein normalization using AzureRed Total Protein Stain to 300 and 500 Imagers

Scientists are Raving about Azure Imagers

Whole department appreciates them

— John Daum, Oklahoma Medical Research Foundation
"The Azure 600 Western blotting imaging system. Sensitive detection, intuitive software. Great for our NIR, fluorescence and chemiluminescent western blot detection. Multiplexing works great! Also a superior system to document our nucleic acid gels. The whole department appreciates them (we have two)."

Fits our needs perfectly

— Karen Terry, Department of Surgery, Duke University
"The Azure 300 is a wonderful gel imager and fits our needs perfectly. It's compact and sleek - looks great on the bench. We just received it and are getting ready to take the first images soon. With the camera upgrade from the Azure 200 the images should be crisp and publication worthy. A solid and well-built instrument."

Crisp bright images of our gels

— Liza Nguyen, New Mexico Consortium
"Before getting [the Azure 400], our group was using an older model without luminescence capability. We upgraded to this machine and it was very easy to use, has the capabilities that we were looking for, and has given crisp bright images of our gels."

Wonderful instrument! Terrific value and customer support!

​—John Flanagan, Civetta Therapeutics​
“We’ve been very pleased with the Azure 600 Gel Imaging System. The quality and limit of detection for both the chemiluminescence and near-IR images is outstanding. Image acquisition is straightforward and user-friendly. The after-sales support is top notch – as there have been additional software upgrades and peripheral devices that were rolled-out post purchase. We’ve been happy with the new features. Our main contact at Azure (Vic Gagne) has been amazing. What sets this system apart from some of the bigger vendors is the ease-of-use and the personalized customer support. If your lab or core facility is looking for an imaging system, I highly recommend the Azure 600 Gel Imaging System.“

I love it and have been incredibly happy with the machine and Azure as a company​

— Matthew Buccili, PEEL Therapeutics​
“The c600 has been an essential workhorse in the lab since the day we bought it. With countless westerns and more than a fair share of nucleotide gels being imaged and analyzed using it. I greatly appreciate being able to switch quickly between applications and methods, as well as not needing proprietary software to view my data. It’s been given 4/5 stars for ease of use only because you need to know how to ask the software what you want it to show you, which can be a bit of a learning curve. Once you understand the software though you can dial in your settings much more easily than with other machines I’ve used. It also offers a more push and capture option when you’re expecting a strong response and just want to capture an image. I’ve been very happy with how their program balances weak signals and stronger signals since I’m often using the same blot for 7-10 proteins. With aftercare, Azure has been fantastic! They check in to make sure everything is going well, and to see if they can help with anything more just enough that it’s not intrusive but often enough that you don’t worry that they forgot about you.“

Ready to learn more about Azure Imagers?

Set up a demo! We'd love to meet with you and your lab.

FluorChem is a registered trademarks of ProteinSimple. No endorsement is implied by the use of these marks. All rights reserved.

Documents

Document TypeDescription
BrochureAzure Imager BrochureDOWNLOAD
BrochureAzure Imaging Systems Model ConfigurationsDOWNLOAD

Review of the Azure 600 from SelectScience

“We’ve been very pleased with the Azure 600 Gel Imaging System. The quality and limit of detection for both the chemiluminescence and near-IR images is outstanding. Image acquisition is straightforward and user-friendly. The after-sales support is top notch – as there have been additional software upgrades and peripheral devices that were rolled-out post purchase. We’ve been happy with the new features. Our main contact at Azure (Vic Gagne) has been amazing. What sets this system apart from some of the bigger vendors is the ease-of-use and the personalized customer support. If your lab or core facility is looking for an imaging system, I highly recommend the Azure 600 Gel Imaging System.”

—John Flanagan, Civetta Therapeutics
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